黄单胞菌属细菌非编码小RNA的研究进展

Research Progress on Small Non-coding RNA of the Xanthomonas spp.

黄单胞菌属(Xanthomonas)是一类能引起多种单子叶和双子叶植物感病的革兰氏阴性细菌,严重危害水稻、甘蓝、番茄、柑橘等多种作物,其入侵和增殖依赖于三型分泌系统(Type III Secretion System,T3SS)和其他毒素因子。细菌非编码小RNA能通过与靶m RNA互作,在转录后水平调控基因的表达,或直接与蛋白互作,影响细胞的各种生理功能。主要介绍了细菌非编码小RNA的分类、及其对细菌蛋白调节、生长代谢、基因转录以及毒力调控等方面的研究进展,并重点对黄单胞菌属细菌已鉴定的非编码小RNA及其生物学功能进行综述,以期为黄单胞菌引起的作物病害防控提供新的思路。

The gram-negative plant-pathogenic bacterium of the genus Xanthomonas infects a variety of monocotyledonous plants and dicotyledonous plants, such as rice, cabbage, tomato, citrus and other economic crops. Type III secretion system and other virulence determinants contribute to the infection and proliferation of Xanthomonas. The majority of bacterial small non-coding RNAs （ sRNAs ） modulates the expression of target mRNAs by base pairing mechanisms, or affects various physiological functions of the cell by binding directly with the protein. This review summarizes the recent study advances in the classification and the effects of sRNA on bacterial protein regulation, metabolism, transcription and virulence regulation, focusing on the identified sRNAs of Xanthomonas and their biological functions, which aims at providing new ideas for controlling crop＇ s diseases caused by Xanthomonas.