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非小细胞肺癌脑转移患者头部放疗配合口服凯美纳疗效与不良反应观察 被引量:6

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摘要 目的探讨非小细胞肺癌脑转移患者头部放疗配合口服凯美纳疗效与不良反应。方法选取我院收治的28例非小细胞肺癌脑转移患者,采取随机数字表法均分为观察组和对照组各14例。对照组采取全脑放疗或全脑放疗加肿瘤局部加量放疗,观察组在头部放疗的基础上联合凯美纳口服进行治疗。结果 2组的完全缓解率,部分缓解率,疾病稳定率和疾病进展率差异均有统计学意义(P<0.05)。2组客观有效率和疾病控制率差异均有统计学意义(P<0.05)。观察组皮疹和腹泻的发生率显著高于对照组,头痛、脱发、白细胞减少发生率较对照组显著降低,差异均有统计学意义(P<0.05)。结论头部放疗配合口服凯美纳治疗非小细胞肺癌脑转移的疗效显著优于单纯头部放疗者,且凯美纳可有效减少脱发、白细胞减少、头痛等神经系统症状。
出处 《中国实用神经疾病杂志》 2016年第20期75-76,共2页 Chinese Journal of Practical Nervous Diseases
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