表皮生长因子与红外线照射对伤口愈合的疗效比较

目的观察对比重组人表皮生长因子（rhEGF）与红外线照射促进伤口愈合的临床疗效。方法286例皮肤创伤经清创术后随机分为两组，A组每日使用rhEGF治疗，B组每日进行红外线照射治疗，观察创面愈合时间、创面愈合质量、瘢痕增生情况。结果A组创面愈合时间（6．76±1．83）d较B组（7．52±1．61）d缩短，A组愈合良好率88．1％高于B组的72．7％，A组瘢痕组织增生发生率2．1％低于B组的7．7％，差异具有统计学意义（P〈0．05）。结论rhEGF治疗与红外照射治疗相比能缩短皮肤创伤的愈合时间，提高创面愈合质量，减少瘢痕增生，有重要临床应用价值。

Objective To observe and compare the clinical effect of recombinant human epidermal growth factor （ rhEGF ） and infrared irradiation on wound healing. Method 286 cases of skin wound after debridement were randomly divided into two groups： group A were daily given recombinant human epidermal growth factor （ rhEGF ） treatment, while group B received daily infrared irradiation treatment, observed the time of wound healing, the quality of wound healing and scar hyperplasia. Results The wound healing time in group A was shorter than that in group B, the quality of wound healing was improved, the incidence of scar hyperplasia was decreased, and significantly statistical differences could be found （ P〈0.05 ） . Conclusions Study results indicate that recombinant human epidermal growth factor （ rhEGF ） treatment can shorten the healing time of skin trauma, improve the quality of wound healing and reduce sear hyperplasia. So it absolutely has important clinical application value.