消痤饮联合异维A酸治疗中重度痤疮的临床疗效观察

目的观察消痤饮联合异维A酸治疗中重度痤疮的临床疗效。方法将确诊的120例中重度痤疮患者随机分成观察组、对照1组、对照2组，每组各40例。观察组予中药消痤饮加减联合异维A酸治疗，对照1组单纯予西药异维A酸治疗，对照2组单纯予中药消痤饮加减治疗。以上患者连续治疗8周后观察疗效。结果观察组总有效率为80％，对照1组总有效率为55％，对照2组总有效率为57．5％；观察组疗效明显优于对照1组、对照2组，差异有统计学意义（P〈0．01，P〈0．05），对照1组与对照2组疗效差异无统计学意义（P〉0．05）。结论消痤饮联合异维A酸治疗中重度痤疮疗效显著，值得推广。

Objective To observe the clinical effect of treating moderate and severe acne with combination of Xiao Cuo Yin and 13-cis-retinoic acid. Methods 120 patients with moderate and severe acne were randomly divided into 3 groups, 40 cases in treatment group treated with Xiao Cuo Yin and 13-cis-retinoic acid, 40 cases in control group 1 treated with 13-cis-retinoic acid and 40 cases in control group 2 treated with Xiao Cuo Yin. These patients were observed the effect after continuously treatment for 8 weeks. Results The total effective rates of treatment group, control group 1 and control group 2 were 80%, 50%, 57.5%.There was a significant difference between treatment group and control group 1, control group 2, and no significant difference between control group 1 and control group 2. Conclusion The combination of Xiao Cuo Yin and 13-cis-retinoic acid has a significant curative effect on moderate and severe ache.