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冠心病及其易感因素的相关性研究 被引量:4

Correlation Study on the Coronary Heart Disease and Its Predisposing Factors
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摘要 目的探讨冠心病易感因素中的独立危险因素,对冠心病早期防治提供有益的临床依据。方法回顾性分析我院2014年1月1日—2016年1月1日的冠心病组患者共322例,对照组356例,记录患者一般资料、吸烟情况、饮酒情况、血脂水平、合并高血压症、高血脂症、高血糖症情况并统计组间差异,多因素回归分析环境因素对冠心病易感性的影响。结果对照组与冠心病组相比,年龄、吸烟情况及高密度脂蛋白水平差异均存在统计学意义(P<0.05);多元回归分析显示,吸烟患者、高密度脂蛋白水平降低及糖尿病患者患冠心病风险分别提高1.9倍、3.0倍和3.4倍。结论年龄、吸烟情况、糖尿病和高密度脂蛋白降低是冠心病发病的独立危险因素。 Objective To investigate the independent risk factors of coronary heart disease(CHD),and to provide a useful basis for early prevention and treatment of coronary heart disease.Methods Retrospective analysis of CHD and control from January 1,2014 to January 1,2016.The number of CHD group were 322 cases,and that of the control group were 356 cases.Records of patients with general information,the situation of smoking and drinking,blood lipid levels,with differences in hypertension,hyperlipidemia,hyperglycemia.Influence of environmental factors on susceptibility to coronary heart disease were analysis by multivariate regression analysis.Results Compared with the control group,age,smoking and high density lipoprotein levels were significant differences in the case group(P〈0.05);multiple regression analysis showed that smoking patients,high density lipoprotein levels in patients with diabetes and reduce the risk of coronary heart disease increased by 1.9 times,3.0 times and 3.4 times respectively.Conclusion Age,smoking,diabetes and high density lipoprotein cholesterol were independent risk factors for coronary heart disease.
作者 吴歌 李贵斌 张冬青 WU Ge LI Guibin ZHANG Dongqing(Clinical Medicine Department, The Fourth Hospital of Jilin University, Changchun Jilin 130011, China Orthopaedic Department Cardiology Departmet)
出处 《中国卫生标准管理》 2017年第4期26-28,共3页 China Health Standard Management
基金 吉林省卫生厅课题资助(2016Q015)
关键词 环境因素 冠心病 易感因素 吸烟 environmental factors coronary heart disease predisposing factors smoking
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  • 1郭永和,张维君,周玉杰,赵冬,周志明,张红.冠状动脉造影患者心血管病危险因素与冠状动脉病变程度的相关性分析[J].中华心血管病杂志,2005,33(5):415-418. 被引量:73
  • 2Rachel Huxley,Federica Barzi,Mark Woodward,杨靓(译),刘靖(校).男性与女性糖尿病患者致死性冠心病的额外危险:37个前瞻性队列研究的汇总分析[J].英国医学杂志中文版,2006,9(3):146-149. 被引量:10
  • 3江时森,吕磊,Crag Juergens,宫剑滨,王立军,彭永平,徐东进,黄浙勇.中国人和澳大利亚人冠状动脉病变对比研究[J].中华心血管病杂志,2007,35(5):447-450. 被引量:14
  • 4Vlassara H.Recent progress in advanced glycosylation end products and diabetic complications.Diabetes,1997,46(Suppl 2):19-25.
  • 5Peppa M,Uribarri J,Vlassara H.The role of advanced glycosylation end products in the development of atheroscleosis.Curr Diab Rep,2004,4(1):31-60.
  • 6宋涛.糖基化终末产物对心血管系统的损伤机制及干预措施.湖南:中南大学,2007:61-66.
  • 7Panagiotopoulos SO,Brien RC,Bucala R.Aminoguanidine has an anti-atherogenic effect in the cholesterol-fed rabbit.Atherosclerosis,1998,136(1):125-131.
  • 8Chang KC,Tseng CD,Wu MS,et al.Aminoguanidine prevents arterial stiffening in a new rat model of type 2 diabetes.Eur J Clin Invest,2006,36(8):528-535.
  • 9Wu MS,Liang JT,LinYD,et al.Aminoguandine prevents the impairment of cardiac pumping mechanics in rats with streptozotocin and nicotinamide-induced type 2 diabetes.Br J Pharmacol,2008,154(4):758-764.
  • 10Zheng F,Zeng YJ,Plati AR,et al.Combined AGE inhibition and ACEI decreases the progression of established diabetic nephropathy in B6 db/db mice.Kidney int,2006,70(3):507-514.

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