胎膜早破与新生儿感染的临床分析

Clinical Analysis of Premature Rupture of Membranes and Neonatal Infection and Application of Antibiotics

目的分析胎膜早破与新生儿感染的临床关系及抗菌药物的应用。方法本研究所选对象为我院收治的100例胎膜早破孕妇,回顾性分析分析胎膜早破与新生儿感染的临床关系。结果全部100例孕妇中,共有10例新生儿发生感染,感染发生率为10.0%(10/100),包括6例下呼吸道感染,2例皮肤感染,1例眼部感染和1例为肠道感染;随着孕周降低和破膜时间延长,新生儿感染发生率上升,胎膜早破后选择剖宫产术也会让新生儿感染发生率增加;全部10例发生感染的新生儿中,共检出13株病原菌,包括5株大肠埃希菌,3株金黄色葡萄球菌,2株白色假丝酵母菌,2株溶血性链球菌,1株其他。结论新生儿感染和胎膜早破的发生时间、分娩方式和胎儿孕周有直接关系,临床中应早期诊断。

Objective To analyze the clinical application and the relationship between premature rupture of neonatal infection and antibiotics. Methods This study selected objects for 100 cases in our hospital were premature rupture of fetal membranes of pregnant women, retrospective analysis of premature rupture of membranes and its relationship with clinical features of neonatal infections. Results All the 100 cases of pregnant women, 10 cases of neonatal infection, the infection rate was 10% （10/100）, including 6 cases of lower respiratory tract infection, 2 cases of skin infection, 1 cases of ocular infection and l cases of intestinal infection; analysis found that with gestational weeks and reduce the rupture time, neonatal birth rate increased significantly, premature rupture of membranes choose cesarean section will make neonatal infection rate increase; all 10 cases of infection in neonates, 13 bacterial isolates, including 5 strains of Escherichia coli, 3 strains of Staphylococcus aureus, 2 strains ofcandida albicans, 2 strains of Streptococcus hemolyticus bacteria, 1 strains of other. Conclusion The time of occurrence of neonatal infection and premature rupture of membranes, mode of delivery and fetal gestational week directly, early diagnosis should be in clinical.