自贡市第四人民医院乳腺癌患者术后化疗感染情况分析

Risk Factors for Infections in Breast Cancer Patients after Surgery

目的:探讨自贡市乳腺癌患者在术后化疗巩固治疗后发生的感染情况,并对其进行分析,为临床感染预防工作提供理论依据。方法:研究分析2014年6月至2016年3月于我院进行手术化疗后发生感染的32例乳腺癌患者,留取患者包括口腔溃烂组织、血液、尿液等标本,进行细菌鉴定以及药敏试验。结果:32例乳腺癌患者术后化疗中59.3%感染出现在第2~3疗程;感染共40例次,感染类型以呼吸道感染为主,20例次占50%,消化道感染与皮肤软组织感染各占8例次,各占20%;32例感染患者检出病原菌56株,以革兰阴性菌30株,占53.6%,革兰阳性菌株、真菌株分别占28.6%和17.9%。结论:乳腺癌术后化疗患者免疫力降低,是感染的高危人群,感染部位以呼吸道为主,有针对性制定有效的护理对策能够降低感染发生率,可提高治疗效果。

Objective： To explore risk factors for infections in breast cancer patients chemotherapy after surgery in Southwest of China and carries on the analysis in order to provide theoretical basis for clinical infection prevention work. Methods： 56 GERD patients treated in Laoximen community health service center were divided into two groups. The treatment group patients used PPI combined with low intensity aerobic exercise,and the control group patients applied only PPI for treatment. 32 breast cancer patients in chemotherapy after surgery were analyzed on June 6,2014-March 2016. All the materials were researched including oral ulcers,such as blood,urine specimens,to identify the bacteria and drug sensitive test. Results： 32 cases of breast cancer patients after chemotherapy were detected,with infection rate of59.3% during the second and third period of treatment. A total of 40 cases of infection,infection type is given priority to with respiratory tract infection,20 cases（ 50%）,digestive tract infection and skin soft tissue infection,8 cases of each time each accounted for 20%; Pathogen of 32 cases of infection were detected 56 strains,with 30 strains of gram-negative bacteria,（ 53.6%）,gram positive strains,fungi strains accounted for 28.6% and 17.9% respectively. Conclusion postoperative breast cancer chemotherapy patients lowered immunity,is people at high risk of infection,the infection is given priority to with the respiratory tract,targeted to develop effective nursing measures can reduce the incidence of infection,can improve the therapeutic effect of treatment. Conclusion： It is the people at high risk of infection,the infection is given priority to with the respiratory tract,targeted to develop effective nursing measures can reduce the incidence of infection,can improve the therapeutic effect.