27例卵巢畸胎瘤的诊断与治疗

Diagnosis and therapy of twenty-seven cases with ovarian teratoma

目的探讨卵巢畸胎溜的早期诊断和防治方法。方法对我院1998—2015年收治的27例卵巢畸胎瘤患者的临床资料进行回顾性分析,观察卵巢畸胎溜的早期诊断和治疗效果。结果早期经B超诊断23例,占85.19%;进一步经CT、MRI、PET或肿瘤标记物等诊断3例;剖腹探查术中诊断1例。早期通过手术切除原发肿瘤、辅助化疗等治愈24例,治愈率为88.89%。1例在就诊时已发生了恶变和多处转移,手术半年后死亡;2例术后多次复发,经反复手术切除原发瘤和转移瘤后治愈。总治愈率高达96.30%。结论卵巢肿瘤防治工作应从儿童和青少年时期开始,要充分利用各种医学影像学、肿瘤标记物、腹腔镜和剖腹手术的机会,力争早发现、早诊断,早期采用综合性防治措施。

Objective To investigate the early diagnosis and prevention methods of twenty-seven cases with ovarian teratoma. Methods The clinical data of 27 patients with ovarian teratoma treated in our hospital from 1998 to 2015 were retrospectively analyzed, and the early diagnosis and treatment of ovarian teratoma were observed. Results Twenty-three cases were diagnosed with ultrasonography at the early stage, accounting for 85.19%; three cases were further diagnosed with CT, MRI, PET and tumor marker; one ease was diagnosed with exploratory laparotomy. Twenty-four cases were cured by early surgical resection of primary tumors and adjuvant chemotherapy, the cure rate was 88.89%;1 case had a malignant transformation and multiple metastases at the time of visit, and died six months after surgery; 2 eases of multiple recurrence were cured after repeated surgery to remove the primary tumor and metastases. The total cure rate was 96.30%. Conclusion Prevention and treatment of ovarian cancer should start from childhood and adolescence. To make full use of a variety of medical imaging, tumor markers, laparoseopie and laparotomy opportunities, and strive to early detection, early diagnosis, early use of comprehensive prevention and control measures.