自体血回输在全髋关节置换术的临床应用研究

Clinical Application Study of Autologous Blood Transfusion in Total Hip Arthroplasty

目的:探讨自体血回输在全髋关节置换术的临床应用效果。方法:选取2015年12月-2016年12月本院收治的腰硬联合麻醉下骨科全髋关节置换术患者ASAⅠ~Ⅲ级患者60例作为研究对象,按照随机数字表法将其分为观察组和对照组,每组30例。对照组根据术中出血情况仅输注异体血,观察组根据术中出血情况回收式自体输血,对比分析两组患者手术前后的血常规、手术前后的凝血4项、输血量以及术后引流量。结果:观察组患者手术前的血常规以及凝血4项与对照组相比差异均无统计学意义(P>0.05)。手术后的血常规、凝血4项以及输血量以及术后引流量与对照组比较差异均有统计学意义(P<0.05)。结论:与异体输血相比,自体血回输在全髋关节置换术中安全性高,临床效果显著,值得临床推广应用。

Objective： To investigate the clinical effect of autologous blood transfusion in total hip arthroplasty （ THA ） .Method： A total of 60 ASA Ⅰ-Ⅲ cases undergoing total hip arthroplasty under general anesthesia combined with spinal and epidural anesthesia, who admitted in our hospital from December 2015 to December 2016, were divided into the observation group and the control group according to random number table method, 30 cases in each group.In the control group, allogeneic blood was infused only according to the operation blood loss.Autologous blood was transfused in the observation group according to the blood loss during operation.The blood routine and operation 4 before and after coagulation, blood transfusion volume and postoperative drainage volume of two groups were compared before and after operation.Result： The differences of blood routine and blood coagulation of two groups before operation were no statistically significant （ P〉0.05 ） .The differences of blood routine, blood clotting, blood transfusion volume and postoperative drainage volume of two groups were statistically significant （P〈0.05） .Conclusion： Compared with allogeneic blood transfusion, autologous blood transfusion in total hip arthroplasty possess high safety and significant clinical effects, it is worthy of clinical application.