乌司他丁、奥曲肽联合应用于急性胰腺炎30例的疗效与A-PACHEⅡ分析

Ulinastatin and octreotide for curative effect analysis of APACHE Ⅱ and 30 cases of acute pancreatitis patients

目的:探究乌司他丁、奥曲肽联合应用于急性胰腺炎30例的疗效与APACHEⅡ。方法:研究对象是2014年9月~2016年9月来我院就诊的60例AP患者,按照治疗采用的药物不同划分为例数相同的两组,单一组(n=30)与联合组(n=30),单一组单纯采用奥曲肽治疗,联合组在单一组基础上采用乌司他丁治疗,对比两组治疗效果与APACHEⅡ评分。结果:联合组总治疗有效率93.33%(28/30)显著高于单一组的83.33%(25/30)(λ2=3.864,P=0.026<0.05);治疗后联合组APACHEⅡ评分(5.87±0.34)分显著低于单一组的(7.95±0.34)分(t=3.541,P=0.032<0.05)。结论:两种药物联合运用于急性胰腺炎治疗,效果显著,而且有效改善APACHEⅡ评分,值得在急性胰腺炎患者治疗过程中推广应用。

Objective：to explore the ulinastatin,octreotide combined applied to the curative effect of 30 cases of patients with acute pancreatitis with APACHE Ⅱ. Methods：to select the research object is in September 2014 ~ September 2016 to our hospital during the period of 60 patients with AP,according to the drugs used in the process of treatment is divided into different cases of the same in the two groups,a single set of（n=30） and joint group（n=30）,a single set of patients with pure peptide treatment using Mr Song,united in a single group on the basis of using ulinastatin treatment,compared two groups of treatment effect with APACHE Ⅱ score. Results：joint group total effective rate was 93.33%（28/30） was significantly higher than treatment single group 83.33%（25/30）（λ2=3.864,P=3.8640.05）; Joint group after treatment with APACHE Ⅱ score（5.87±0.34） significantly lower than that of single group（7.95±0.34）points（t=3.541,P=3.5410.05）. Conclusion：the combination of both drugs used in treatment of patients with acute pancreatitis,the effect is remarkable,and effectively improve the APACHE Ⅱ score,is worthy of popularization and application in the process of treatment of patients with acute pancreatitis.