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标准剂量瑞舒伐他汀与阿托伐他汀治疗不稳定型心绞痛的疗效分析 被引量:1

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摘要 目的:分析标准剂量瑞舒伐他汀与阿托伐他汀治疗不稳定型心绞痛的疗效。方法:采用随机数字表法将商丘市民权县李堂卫生院2014年1月~2015年2月119例不稳定型心绞痛患者进行分组,对照组59例给予阿托伐他汀口服,观察组60例给予瑞舒伐他汀口服,对比两组临床疗效及血脂指标。结果:观察组治疗后总有效率93.33%高于对照组的79.66%,P<0.05;观察组治疗后TC、TG、LDL-C、HDL-C指标改善幅度均优于对照组,其中,TC、LDL-C指标与对照组比较,P<0.05。结论:瑞舒伐他汀能够通过抑制HMG-CoA还原酶,加快LDL的吸收及分解,抑制VLDL的合成,降低血脂水平,改善心肌缺血及临床症状,治疗不稳定型心绞痛效果优于阿托伐他汀,值得临床推广。
作者 李学斌
出处 《北方药学》 2017年第3期143-143,142,共2页 Journal of North Pharmacy
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