超声提取苦参中的苦参碱和氧化苦参碱

Ultrasonic Extraction of Matrine and Oxymatrine from Sophora Flavescens

本文研究了超声法提取苦参中的苦参碱和氧化苦参碱,探讨了溶媒、超声时间和温度对它们提取效果的影响。实验结果表明纯水对苦参碱和氧化苦参碱的提取效果优于乙醇溶液。在纯水用量是苦参饮片质量的10倍,超声时间为45 min,温度为80℃的条件下,苦参碱和氧化苦参碱的总浸出率达46.54%。

The technology of ultrasonic extraction was used to extract matrine and oxymatrine from Sophora flavescen. The effects of the kind and dosage of solvent, ultrasound time and temperature on the total leaching rate of matrine and oxymatrine were investigated. It is found that choosing water as solvent to ultrasonic extract matrine and oxymatrine from Sophora flavescens is better than ethanol solution. The total leaching rate of matrine and oxymatrine is up to 46.54 % under the conditions of 10：1 of solvent to solid ratio of water to Sophora flavescens, 45 rain of ultrasound time and 80℃ of ultrasound temperature.