摘要
苦参碱(Matrine)是从苦参中提取出来的一种生物碱,已报道苦参碱具有多种药理作用,包括抗炎,免疫调节等。目前研究表明,苦参碱对中枢神经系统具有解热、镇痛、抗惊厥、稳定神经等作用;对心血管系统具有明显的负性频率和正性肌力的作用,有防治动脉粥样硬化、减轻心肌损伤的功能;对消化系统能够起到抗肝损伤、抗纤维化的效果;除此之外还具有抗肿瘤、抗肝癌的效果。本文就苦参碱近年的研究做一综述。
Matrine,isolated from Sophora flavescens Ait.（ Kushen）,has been found to possess a variety of pharmacological effects,including anti-inflammation and immunity-regulation activity. Now,the research of matrine is most widely. Matrine can antipyretic,analgesic,anticonvulsant,stabilize nervous system on the central nervous system; and on the cardiovascular system,matrine has negative frequency and positive inotropic effect,can prevent atherosclerosis,reduce the role of myocardial injury; on the digestive system,matrine can anti-liver injury,anti-fibrosis,elevated white blood cell etc; matrine also has anti-tumor, anti-liver cancer effects. This article seeks to summarize the effect of matrine.
出处
《成都中医药大学学报》
2017年第1期123-127,共5页
Journal of Chengdu University of Traditional Chinese Medicine
