改良羊膜移植法治疗农牧业翼状胬肉的疗效观察

Observation on the curative effect of modified amniotic membrane transplantation for agricultural pterygium

目的:观察改良羊膜移植法治疗农牧业翼状胬肉的疗效。方法:选取276例初发翼状胬肉的患者(276眼),按照随机数表法将其分为传统组与改良组,每组138例。传统组采用翼状胬肉切除联合自体结膜移植术;改良组采用改良羊膜移植法,观察两组患者治疗效果。结果:两组患者经过1年的随访,传统组治愈122例,复发16例,治愈率为88.41%;改良组治愈131例,复发7例,治愈率为94.93%,改良组治愈率优于传统组,差异具有统计学意义(x^2=5.02,P<0.05)。结论:改良羊膜移植法操作简单,对眼部损伤小,可尽量保留结膜组织,提高手术成功率,是治疗翼状胬肉的有效手段。

Objective： To observe the curative effect of modified amniotic membrane transplantation for agricultural pterygium. Methods： A total of 276 cases（276 eyes） with early pterygium were randomized divided into traditional group（138 cases） and modified group（138 cases） as random table. The traditional group was treated with pterygium excision in combination with autologous conjunctival transplantation; the modified group was treated with modified amniotic membrane transplantation; to observe the curative effect of the two groups. Results： After all of patients were followed up for 1 year, 122 cases were cured and 16 cases were recurrence, and the recovery rate was 88.41% in traditional group; 131 cases were cured and only 7 cases were recurrence, and the recovery rate was 94.93% in modified group and was better than traditional group; the difference between the two groups was statistical significant（χ2=5.02, P〈0.05）. Conclusion： The modified amniotic membrane transplantation method is simple in operation, mini invasive for eye tissue, and can retain conjunctival tissue in utmost; it also can improve success rate of surgery and be an effective mean for treatment of pterygium.