超声造影在类风湿关节炎中的应用进展

The application and progress of contrast-enhanced ultrasound in rheumatoid arthritis

超声造影是一项评估软组织血流的超声技术,目前在大部分超声仪器中均配备该功能。超声造影不仅能够定性及半定量的评估血流,还可作定量分析。目前超声造影在临床主要用于在心血管显像及肿瘤的血流灌注评估。为此,研究概述超声造影在类风湿关节炎的临床研究与应用;常用超声造影剂及其使用剂量及方法;目前使用超声造影的评估滑膜炎的方法及相关参数;超声造影剂在类风湿关节炎中的研究进展。通过参数、指标及方法比较,提出超声造影在类风湿关节炎临床应用中存在局限性,应用价值有待探索。

The contrast-enhanced ultrasound（CEUS） been equipped in most commercial ultrasound system, is a newer technology which could evaluate the blood flow of soft tissue. It could not only make qualitative and semi-quantitative analysis, but also the quantitative analysis could be acquired. At present, it has been applied on cardiovascular imaging and tumor perfusion assessment in clinical. The clinical usage of CEUS in rheumatoid arthritis（RA） was summarized in the paper which included its common clinical type, dose of ultrasound contrast agent and various method of usage described. Besides, the paper not only introduced the evaluation of the synovitis in RA with the parameters resulted from CEUS, but also illuminated the progress of the researches. Through compared these parameters, indexes and methods, this summary revealed the limitation and application value of CEUS to RA, and more exploration need be done in future.