基于贻贝仿生化学的分离功能材料

Separation Materials Based on Mussel-Bioinspired Surface Chemistry

贻贝仿生的表面化学是近年来材料学、化学、生物医学等领域的交叉研究热点。多巴胺可以作为贻贝足丝蛋白(Mfp)超强黏附特性的模型分子,通过复杂的氧化-自聚和组装,形成多种功能的聚多巴胺(PDA)纳米涂层和纳米粒子,在分离膜、吸附材料、生物医用材料、生物黏结剂等领域有着广阔的应用前景。本研究小组近年来持续开展了基于贻贝仿生化学的分离功能材料制备与结构调控的研究工作,率先将多巴胺表面沉积方法应用于多孔分离膜表面的构建与功能化,提出了多巴胺的自聚-沉积过程模型,进而验证了PDA沉积层的纳滤分离特性,建立了一条简单方便的膜表面功能化与纳滤膜制备新途径。本文主要对基于贻贝仿生化学的分离功能材料,特别是分离膜的研究进展进行综述,并对将来的发展趋势进行展望。

In the past decade,mussel-bioinspired surface chemistry has been an interdisciplinary research hotspot in material science,chemistry and biomedicine etc.Dopamine behaves like mussel foot proteins and is able to develop into polydopamine（PDA）nanocoating and nanoparticles with various functions by complicated oxidation,self-polymerization and further self-assembly.PDA nanomaterials have found a variety of applications in separation,adsorption,biomedical and bioadhesives etc.In recent years,we have made many efforts on the preparation and structure control of mussel-bioinspired separation materials.In our works,for the first time,mussel-inspired PDA deposition was introduced to surface construction and functionalization of polymeric porous membranes.A simple model on dopamine evolution and deposition on solid-liquid interface was proposed.Furthermore,a novel thin-film composite nanofiltration（NF）membrane with PDA coating as the active separation layer was developed.These works pioneered a new and simple way of membrane surface functionalization and NF membrane preparation.The aim of this article is to review and highlight the progress of mussel-bioinspired separation materials,especially polymeric separation membranes.