早产极低出生体重儿早期应用不同剂量氨基酸的临床观察

Clinical observation of early application of different doses of amino acids in very low birth weight infants

目的观察早产极低出生体重儿早期应用不同剂量氨基酸的临床效果。方法选取2014年1月~2016年10月我院新生儿科早产极低出生体重儿120例为研究对象,根据氨基酸不同用量分为A、B、C 3组,每组各40例。A组40例患儿给予高剂量氨基酸治疗,B组40例患儿给予中剂量氨基酸治疗,C组40例患儿给予低剂量氨基酸治疗,观察比较3组患儿的临床效果。结果 A组患儿在能量摄入,蛋白质合成,各症状恢复时间以及体重、身长、头围均优于B、C组,差异均有统计学意义(均P<0.05);3组患儿的并发症比较,差异均无统计学意义(均P>0.05)。结论早产极低出生体重儿早期应用高剂量氨基酸,对促进患儿身体发育具有重要作用。

Objective To analyze the cl inical effect of early appl ication of different doses of amino acids in very low birth weight infants. Methods During the pe riod from January 2014 to October 2016 in our hospital neo-natal premature very low birth weight infants 120 cases,given amino acid treatment to children,according to the ap-plication of different doses of amino acids were divided into three groups, including 40 cases of A group of children with high doses of amino acid treatment,B group of 40 cases with middle dose of amino acid treatment,C group of 40 cases the low dose of amino acid treatment, clinical effects were compared between the three groups. Results A group of energy intake and protein synthesis than B and C group？ the symptom recovery time than B,C group shortened, weight,length and head circumference than B and C group increased significantly（P〈0. 05）; com p l ica -tions were compared between the three groups（P〉0. 05）. Conclusion The early application of high dose amino acids in premature infants with very low birth weight can promote the recovery of children,and the clinical effect is significant.