阴式子宫切除术中应用右旋美托咪啶联合低浓度罗哌卡因腹横肌膜神经阻滞的有效性及安全性

Efficacy and safety of dexmedetomidine combined with low concentration ropivacaine on transabdominal sarcolemma nerve block for women with vaginal hysterectomy

目的:探究阴式子宫切除术中应用右旋美托咪啶+低浓度罗哌卡因腹横肌膜神经阻滞的有效性及安全性。方法:选取本院接受阴式子宫切除术治疗妇女120例,按照数字表法随机分为低浓度组、高浓度组各60例,分别给予右旋美托咪啶0.5μg/kg+罗哌卡因0.15%、右旋美托咪啶0.5μg/kg+罗哌卡因1.5%进行麻醉处理,对比分析两组感觉及运动神经阻滞情况及生命体征变化情况。结果:低浓度组麻醉后HR、MAP、VAS评分与高浓度组相比未见差异(P>0.05),感觉恢复时间(233.3±10.1min)和运动恢复至Bromage0级时间(210.7±10.3min)优于对照组(293.5±11.4min、265.5±11.7min)(均P<0.05)。结论:阴式子宫切除术中应用右旋美托咪啶+低浓度罗哌卡因腹横肌膜神经阻滞的效果较好,安全性高。

Objective： To explore the efficacy and safety of dexmedetomidine combined with low concentration ropivacaine on transabdominal sarcolemmal nerve block in vaginal hysterectomy. Methods： One hundred and twenty patients undergoing vaginal hysterectomy were randomly divided into low concentration group and high concentration groupbyrandom number table, and each group had 60 patients, which were anesthetized with dexmedetomidine 0.5μg/kg combined with ropivacaine 0.15% or dexmedetomidine 0.5 μg/kg combined with ropivacaine 1.5%, respectively. Sensory and motor nerve blockage, vital signs of the included patients was compared between the two groups. Results： HR, MAP, VAS score of patients after anesthesia had no significant difference between the two groups （P 〉 0.05）.Sensory recovery time （233.3±10.1min） and the recovery time of Bromage 0 （210.7± 10.3min） of patients in low concentration group were significantly better than those（293.5±11.4rain and 265.5± 11.7 min）of patients in high concentration group （P〈0.05）. Conclusion： Dexmedetomidine combined with low concentration ropivacaine used for transabdominal sarcolemma nerve block in vaginal hysterectomy has excellent effectiveness and safety.