宁南山区回族心血管疾病患者血清同型半胱氨酸浓度分析

Analysis of Serum Homocysteine Levels of Hui Patients with Cardiovascular Disease in Mountainous Areas of Southern Ningxia

目的研究宁南山区回族血清同型半胱氨酸(Hcy)浓度与心血管疾病的关系。方法选择宁南山区回族心血管疾病患者70例,其中心绞痛34例,心肌梗死36例,健康老年人60例,采用美国贝克曼AU5800生化分析仪分别检测各组血清Hcy浓度,比较分析检测结果。结果心绞痛组与心肌梗死组Hcy浓度水平明显高于正常对照组(P<0.05),心绞痛组,心肌梗死组高Hcy血症比例明显高于正常对照组(P<0.05)。结论血清Hcy增高与心血管疾病相关,高浓度Hcy是冠心病的独立危险因素之一。

Objective To research the relationship between cardiovascular disease and serum homocysteine（ Hcy） of Hui patients in mountainous areas of southern Ningxia. Methods 70 patients with cardiovascular disease were selected as Experimental Group（ including 34 patients with angina and 36 patients with myocardial infarction）. The Normal Group had 60 healthy old patients. The Hcy level in the two groups was detected by Beckman AU5800 biochemical analyzer. The results were compared and analyzed. Results The Hcy level of the Experimental Group was significantly higher than that of the Normal Group（ P〈0. 05）. The rate of Hyperhomocysteinemia in the Experimental Group was significantly higher than that in the Normal Group（ P〈0. 05）. Conclusion The high level of serum Hcy is associated with cardiovascular diseases,and it is one of the independent risk factors for coronary heart disease.