原发灶减瘤根治性前列腺切除术治疗骨转移前列腺癌患者的现状及展望(附光盘)

Cytoreductive radical prostatectomy for prostate cancer patients with bone metastases:status and prospect

前列腺癌具有很高的骨转移倾向。目前,国际和国内指南建议骨转移的前列腺癌患者选择全身系统性治疗,不推荐包括根治性前列腺切除术和前列腺放疗在内的局部治疗。近年依据美国SEER数据库和德国慕尼黑癌症登记的研究显示原发灶减瘤手术结合系统治疗可以使骨转移前列腺癌患者生存获益。本文就原发灶减瘤根治性前列腺切除术治疗骨转移前列腺癌患者的现状及展望进行综述。

Prostate cancer has a drift towards bone metastasis. At present, international and Chinese guidelines recom- mend systematic treatment for such patients. However, the latest data from American SEER database and Munich Cancer Reg- istry suggest that such patients could benefit from cytoreductive radical prostatectomy combined with systematic therapy. In this article, we will review the present status of the application of cytoreductive radical prostatectomy and explore its potential im- plications and the future research directions.