饲粮中添加香菇多糖对断奶大鼠生长性能、抗氧化能力和肠道健康的影响

Effects of Lentinan Supplementation on Growth Performance,Antioxidant Capacity and Intestinal Health of Weaned Rats

本研究旨在探讨饲粮中添加香菇多糖对断奶大鼠生长性能、抗氧化能力和肠道健康的影响。试验选取20只健康的断奶Wistar大鼠,按照体重相近的原则分为2个组(每组10只),分别饲喂基础饲粮和添加了84 mg/kg香菇多糖(香菇多糖有效含量为30%)的试验饲粮。试验期为21 d。结果表明:饲粮中添加84 mg/kg香菇多糖显著提高了断奶大鼠的平均日增重和平均日采食量(P<0.05),显著降低了料重比(P<0.05);饲粮中添加84 mg/kg香菇多糖显著提高了断奶大鼠血清和空肠的总抗氧化能力(P<0.05),不同程度降低了血清(P<0.05)和空肠(P=0.08)丙二醛含量;饲粮中添加84 mg/kg香菇多糖显著提高了断奶大鼠空肠黏膜绒毛高度和绒毛高度/隐窝深度(P<0.05);此外,饲粮添加84 mg/kg香菇多糖提高了断奶大鼠盲肠食糜中乳酸菌的数量(P=0.07),显著降低了盲肠食糜中大肠杆菌的数量(P<0.05),并显著提高了盲肠食糜中乙酸、丙酸、丁酸和总挥发性脂肪酸的含量(P<0.05)。综上所述,在断奶大鼠饲粮中添加84 mg/kg香菇多糖(香菇多糖有效含量为30%)可以改善其抗氧化能力、空肠黏膜形态结构和盲肠菌群结构,进而提高生长性能。

This experiment was conducted to determine the effects of lentinan supplementation on growth per- formance, antioxidant capacity and intestinal health of weaned rats. Twenty healthy weaned Wistar rats, based on the similar body weight, were randomly assigned to two group with each group has 10 rats. The rats in those two groups were fed a basal diet and a experimental diet supplemented with 84 mg/kg lentinan （the effective content of lentinan was 30% ）, respectively. The experiment duration was 21 d. The results showed that diet supplemented with 84 mg/kg lentinan significantly increased average daily gain and average daily feed intake （P〈0.05）, and significantly decreased feed to gain ratio of weaned rats （P〈0.05）. Diet supplemented with 84 mg/kg lentinan significantly enhanced the total antioxidant capacity in serum and jejunum （P〈0.05）, and reduced the malondialdehyde content in serum （P〈0.05） and jejunum （P= 0.08） of weaned rats in different degrees. Diet supplemented with 84 mg/kg lentinan also significantly increased the villus height and the villus height/crypt depth of jejunum of weaned rats （P〈0.05）. In addition, diet supplemented with 84 mg/kg lentin- an increased the Lactobacillus number in cecal digesta （P = 0.07 ）, significantly reduced the Escherichia coli number in cecal digesta （P〈 0.05）, and significantly increased the contents of acetate, propionate, butyrate and total volatile fatty acids in cecal digesta of weaned rats （P〈0.05）. These results suggest that diet supple- mented with 84 mg/kg lentinan can improve the antioxidant capacity, jejunal mucosal morphology and cecal microbiota structure, and then increase the growth performance of weaned rats.