中国大陆122例原发性恶性心包间皮瘤临床与超声心动图特征分析

Clinical and echocardiographic features of 122 cases of primary malignant pericardial mesothelioma in China mainland

目的探讨原发性恶性心包间皮瘤（PPM）的临床及超声心动图特征。方法在中、英文数据库检索1981-2015年中国大陆报道且接受超声心动图检查的PPM病例，收集患者的临床和超声心动图特征资料。结果共122例PPM患者纳入本研究，中年（平均39．9±14．7岁）及男性受累为主（79，64．8％）。超声心动图最常见的征象为心包积液（74．6％），而绝大多数积液为血性（97．7％）；其他征象包括心包肿块（36．9％）和心包增厚（18．0％）。超声诊断PPM的符合率为26．2％。结论PPM最常见的超声心动图征象是大量心包积液。超声心动图是筛查和评估PPM的重要检查手段，但确定诊断依赖病理学检查。

Objective To explore the clinical and echocardiographic characteristics of primary malignant pericardial mesothelioma （PPM）. Methods Cases of PPM with description of eehocardiographic presentations from China mainland were searched from database during 1981 to 2015. Data about the clinical and echocardlographic [eatures of the patients were collected. Results A total of 122 patients were included for analysis. It involved mainly middle-aged [（39.9 -＋ 14.7）years] and male patients （79,64.8 %）. The most common echocardiographie demonstration was pericardial effusion （74.6%） with were mostly bloody （97.7%）, followed by pericardial masses （36.9%） and pericardial thickening （18.0%）. The echoeardiographic diagnostic accordance rate was about 26.2%. Conclusions The most common presentation of PPM on echocardiogram is massive pericardial effusion. Echocardiography is of great value in screening and assessment of PPM. The definitive diagnosis is made by histopathologieal examination.