新型负载型催化剂在植物甾醇酯合成工艺中的应用

Application of novel supported catalyst in synthesis process of phytosterol ester

开发了一种新型、高效的纳米羟基磷灰石负载氧化铜催化剂,初步表征了负载型催化剂的性质(比表面积、孔结构、微观形貌及晶体结构),并优化了其催化植物甾醇、脂肪酸合成植物甾醇酯的工艺参数。结果表明:纳米羟基磷灰石经水蒸气扩孔、Cu(NO_3)_2浸渍、焙烧可有效制备氧化铜-纳米羟基磷灰石(Cu O-NHAP)催化剂;酯化最佳条件为催化剂用量0.6%、酸醇摩尔比1.4∶1、反应温度160℃、反应时间6 h,在此条件下酯化率为99.3%;催化剂重复使用6个批次后,催化剂相对活力仍保持在85%以上。

A novel and high efficient copper oxide - nano hydroxyapatite （ CuO - NHAP） catalyst wasdeveloped. The properties of supported catalyst （ specific surface area, pore structure, mcro - morphologyand crystal structure） were characterized and the process parameters of synthesis of plant sterol ester withplant sterol and fatty acid catalyzed by CuO - NHAP were optimized. The results showed that the CuO -NHAP catalyst was prepared effectively by pores - broading of nano - hydroxyapatite with vapour, impreg-nation with Cu （ NO3 ） 2 and calcination. The optimal conditions of esterfication were obtained as follows ：dosage of catalyst 0.6%, molar ratio of oleic acid to phytosterol 1.4： 1, reaction temperature 160℃ andreaction time 6 h. Under these conditions, the esterification rate was 99.3 %. When the catalyst was re-used for six times, its activity kept more than 85%.