摘要
目的探讨牙龈卟啉单胞菌(P.g)的菌毛蛋白(FimA)V亚型基因表达与正畸患者牙龈炎性反应的相关性。方法随机选取61例正畸治疗前牙龈健康的患者,分别收集患者正畸治疗前和戴入矫治器后3个月的龈沟液,用PCR技术检测临床样本中的P.g和FimA V型。结果正畸治疗前与戴入矫治器后3个月的P.g检出率分别是26.23%、73.77%,两者间存在统计学差异(P<0.01);FimA V型的检出率分别是9.84%、26.23%,两者间存在统计学差异(P<0.05)。结论正畸患者在戴入矫治器3个月后,P.g和FimA V型的检出率都与牙龈指数呈现正相关,牙龈指数升高,且FimA V型检出率也随之增加,FimA V型可以引起正畸患者的牙龈炎性反应。
Objective To explore the correlation between the gene expression of FimA genotype V of Porphyromonas gingivais(P.g) and gingival inflammatory in orthodontic patients.Methods Totally 61 patients with healthy gingiva were randomly selected.Their gingival crevicular fluid(GCF) was collected before and 3 months after orthodontic treatment.The content of P.g and FimA genotype V in the GCF was detected with PCR technique.Results The detection rate of P.g and FimA genotype V were 26.23% vs 73.77%,and 9.84% vs 26.23% before and after orthodontic treatment,showing significant difference(P〈0.01,P〈0.05).Conclusion Three months after patients wore appliance,the detection rate of P.g and FimA genotype V were positively correlated to gingival inflammation index.The detection rate of FimA genotype V rose with increased gingival index.FimA genotype V can cause gingival inflammatory in orthodontic patients.
出处
《山东大学学报(医学版)》
CAS
北大核心
2017年第3期59-63,共5页
Journal of Shandong University:Health Sciences
基金
济南市科技局企业创新计划(201121038)
关键词
正畸治疗
牙龈卟啉单胞菌
FimA
V型
牙龈炎
Orthodontic treatment
Porphyromonas gingivais
FimA genotype V
Gingivitis