肝硬化门静脉血栓形成的机制与治疗进展

Advances in mechanisms and treatment of portal vein thrombosis in patients with liver cirrhosis

门静脉血栓(PVT)是指门静脉主干及其门静脉系统分支内形成血栓,是肝硬化的重要并发症之一,肝硬化PVT不仅能加重门静脉高压,增加出血的风险,也可脱落逆行造成小肠急性缺血坏死。针对肝硬化患者PVT形成的机制与治疗的最新观点进行了探讨,提出应根据患者的综合情况选择合适的治疗方案。

Portal vein thrombosis（PVT） refers to thrombosis in the main portal vein and portal vein branches and is an important complication of liver cirrhosis.PVT can aggravate portal hypertension,increase the risk of bleeding,and lead to acute ischemic necrosis of the small intestine in case of shedding or retrograde movement.This article focuses on the new points of view on the mechanisms and treatment of PVT in cirrhotic patients and points out that treatment regimen should be selected based on patients＇ overall conditions.