天津地区无偿献血人群HTLV感染情况调查研究

Investigation on the situation of unpaid blood donors infected with HTLV in Tianjin

目的:了解人类T淋巴细胞病毒(HTLV)在天津地区无偿献血人群中的感染情况。方法:采用双抗原夹心酶联免疫法,检测2015年6至7月天津市无偿献血者样本10 295份血清HTLV抗体,阳性标本经巢式PCR和Western blot法进一步确证。结果:10 295份血清标本有2份初筛阳性,确证为阴性。结论:天津地区无偿献血人群属于HTLV感染低危人群,可暂缓对天津市无偿献血人群进行HTLV常规筛查。

Objective： To understand the situation of unpaid blood donors infected with HTLV in Tianjin. Methods：The serum specimens of 10295 cases of unpaid blood donor were screened using sandwich ELISA. Those who were screened positive were re-inspected using ELISA. Lastly, those who were re-inspected positive were confirmed by NEST PCR and Western blot. Results：The serum specimens of 2 cases of unpaid blood donor were positive, however, these were confirmed negative. Conclusion： The rate of unpaid blood donors infected with HTLV in Tianjin is low-risk. Then, it is not necessary to screen for HTLV of unpaid blood donation population in Tianjin at present.