硝苯地平联合硫酸镁治疗妊娠期高血压疾病临床疗效观察

Clinical curative effect observation of Nifedipine combined magnesium sulfate in treatment of pregnancy-inducedhypertension disease

目的探讨硝苯地平联合硫酸镁治疗妊娠期高血压的临床效果。方法通过对2012年6月至2016年6月在商丘市妇幼保健院治疗的110例妊娠高血压患者进行随机分组,实验组患者应用硝苯地平联合硫酸镁治疗,对照组患者给予硫酸镁治疗,观察比较两组患者治疗效果、收缩压和舒张压差异。结果实验组患者治疗总有效率为98.18%,明显高于对照组的85.45%;实验组收缩压和舒张压下降程度优于对照组,差异具有统计学意义(P<0.05)。结论妊娠期高血压患者采用硝苯地平联合硫酸镁治疗可明显提高治疗效果,降低血压,其具有安全性高、疗效确切等特点,临床值得推广应用。

Objective To investigate the effect of nifedipine combined of magnesium sulfate in the treatment of pregnancy-induced hypertension. Methods From June 2015 to June 2016 in our hospital treatment of 110 patients with gestational hypertension were randomized,nifedipine combined magnesium sulfate treatment group patients and the control group patients give magnesium sulfate treatment,to observe therapeutic effect compare two groups of patients,the systolic blood pressure and diastolic blood pressure difference. Results The total effective rate of experimental group patients was 98. 18%,significantly higher than the control group 85. 45%; Systolic blood pressure and diastolic blood pressure drop degree is better than that of control group,while statistically significant difference（P〈0. 05）. Conclusion Patients with gestational hypertension using nifedipine combined therapy with magnesium sulfate can obviously improve the treatment effect,reduce blood pressure,it has the characteristics of high security,curative effect,clinical worth popularization and application.