影像引导下前列腺定向穿刺活检术的研究进展

Advances in Image-guided Targeted Prostate Biopsy

确诊前列腺癌的金标准无疑是病理组织学检查,影像引导下的前列腺定向穿刺活检又是这当中最有效、最便捷的方式。而基于前列腺特异抗原(prostate specific antigen,PSA)筛查以及6分活检结果的前列腺癌诊断,已经由于其对低度肿瘤的过度诊断和对临床上有意义前列腺癌(格林森评分≥7)的诊断不足遭到批评。所以纵观国内外,影像引导已经增加到先用多参数MRI(multi-parametric magnetic resonance imaging,mpMRI)扫描检出病变组织再进行前列腺定向穿刺活检,包括,in-bornMRI引导,认知融合引导,以及MRI/TRUS融合引导下的活检。本文就一些影像引导下前列腺定向穿刺活检术的研究进展进行综述。

Undoubtedly, pathological findings is the golden standard for diagnosing prostate cancer. As we all know, targeted prostate biopsy under the guidance of image-guiding is the most efficient and the most convenient. Nevertheless,based on prostate specific antigen（PSA）screening and sextant biopsy, has been criticized for both overdiagnosis of low-grade tumors and underdiagnosis of clinically significant prostate cancers（Gleason score ≥7）. So on viewing vertically of both national and abroad,image guidance has been added to perform targeted biopsies of lesions detected on multi-parametric magnetic resonance imaging（mpMRI） scans, including in-boreMRI-guided, cognitive fusion, andMRI/transrectal ultrasound fusion-guided biopsy. This review will examine advances in these image-guided targeted prostate biopsy techniques.