扫频OCT对正常人前房结构双眼间对称性的观察

Swept-source optical coherence tomography analysis of anterior chamber structure interocular symmetry in healthy Chinese subjects

目的 应用扫频光学相干断层扫描（OCT）技术分析正常人双眼前房结构的对称性.方法 描述性研究.招募正常受检者360例（720眼）,记录其年龄、性别,测量左右眼眼轴长度（AL）、眼压（IOP）、瞳孔直径（PD）,使用扫频OCT技术采集角膜体积（CV）、虹膜体积（Ⅳ）、前房体积（ACV）、前房深度（ACD）和水平/垂直位前房宽度（ACWH/ACWV）并计算双眼间差值（△）.采用Pearson检验分析年龄、性别、△AL、△IOP与△CV、△IV、△PD、△ACV、△ACD、△ACWH和△ACWV的相关性,采用配对t检验比较双眼间各参数差异.结果 受检者左右眼AL（P=0.768）、IOP（P=0.274）、CV（P=0.809）、IV（P=0.215）、PD （P=0.098）、ACV （P=0.085）、ACD（P=0.374）、ACWH（P=0.422）和ACWV（P=0.142）差异无统计学意义.双眼间△CV为-22.57～18.65 （0.09＆#177;6.93）mm3;△IV为-6.47～9.15（0.11＆#177;1.63）mm3;△PD为-1.61～2.01（-0.05＆#177;0.52）mm;△ACV为-28.64～55.17（0.66＆#177;7.25）mm3;△ACD为-1.01～0.53（0＆#177;0.11）mm;△ACWH为-0.66～0.57（0.01＆#177;0.20）mm;△ACWV为-1.76～0.85（0.03＆#177;0.26）mm.随年龄增长,双眼间△CV（r=-0.182,P=0.001）和△ACD （r=-0.111,P=0.038）减小.结论 正常人群左右眼的眼前段结构具有良好的对称性.

Objective To analyze by swept-source optical coherence tomography the interocular symmetry of anterior chamber structures in a normal Chinese population.Methods In a destriptive study,both eyes fiom 360 people were enrolled.Age,gender,bilateral axial length （AL）,intraocular pressure （lOP）,corneal volume （CV）,iris volume （IV）,pupil diameter （PD）,anterior chamber volume （ACV）,anterior chamber depth （ACD）,horizontal anterior chamber width （ACWH）,and vertical anterior chamber width （ACWV） were recorded.Interocular differences for each parameter were calculated.Pearson correlation analysis was performed to evaluate the correlation among parameters,and paired t-tests were used to compare the differences in the parameters between right and left eyes.Results The differences in AL （P=0.768）,IOP （P=0.274）,CV （P=0.809）,IV （P=0.215）,PD （P=0.098）,ACV （P=0.085）,ACD （P=0.374）,ACWH （P=0.422）,and ACWV （P=0.142） were not statistically significant between the right and the left eyes.The value △CV （mm3） was 0.09±6.93（-22.57-18.65）,△IV （mm3） was 0.11±1.63（-6.47-9.15）,△PD （mm） was-0.05±0.52（-1.61-2.01）,/△ACV （mm3）was 0.66±7.25（-28.64-55.17）,/△ACD （mm） was 0.00±0.11（-1.01-0.53）,/△ACWH （mm） was 0.01±0.20（-0.66-0.57）,and /△ACWV （mm） was 0.03±0.26（-1.76-0.85）.As age increased,both △CV （r=-0.182,P=0.001） and /△ACD （r=-0.111,P=0.038） decreased.Conclusion There is a significant interocular symmetry of anterior chamber structures in normal subjects.