脾脏窦岸细胞血管瘤的超声造影表现与病理对照分析

Littoral cell angioma of the spleen:correlation between Contrast-enhanced ultrasonographic and pathology features

目的探讨脾脏窦岸细胞血管瘤的超声造影表现与病理学特点。方法经手术病理证实的脾脏窦岸细胞血管瘤患者4例,回顾分析其超声造影表现及病理学表现。结果 4例均为多发病灶,二维超声表现为多发高回声结节,超声造影动脉期结节样增强,实质期逐渐增强,内部低增强。病理检查镜下显示脾窦细胞增生,病灶由大小不等、互相吻合的血管性腔隙组成,表面衬覆单层内皮样细胞。肿瘤细胞免疫表型CD31和CD68均阳性。结论脾脏窦岸细胞血管瘤一般为多发病灶,超声造影增强特征与肿瘤血管的类型和数量有关,能够较准确地反映其病理特点。

Objective To explore the Contrast-enhanced ultrasound and pathologic features of splenic littoral cell angioma. Methods Contrast-enhanced ultrasound and pathologic features of 4 patients with surgery and pathology proven littoral cell angio- ma of the spleen were retrospectively analyzed. Results 4 patients were multiple lesions. Histopathologically, splenic sinus cell proliferation composed of anastomosing vascular channels lined with short columnar or fiat endothelial cells with hemosiderin gran- ules. Immunohistologically. both CD31 and CD68 were positive. Conclusion LCA is generally for multiple lesions. Contrast-en- hanced ultrasound enhancement features relate to the type and amount of tumor blood vessels.