原发性免疫性血小板减少症合并急性心肌梗死1例并文献复习

Acute myocardial infarction in patients with primary immune thrombocytopenia： one case report and literature review

目的探讨原发性免疫性血小板减少症（IrrP）合并急性心肌梗死（AMI）的发病机制、临床特征、治疗及预防方法。方法回顾性分析1例新诊断的ITP合并AMI患者的临床特征、诊疗经过及后期随访，并结合相关文献报道，分析ITP患者发生AMI的高危因素及诊疗方案。结果本例ITP患者存在AMI高危因素，目前ITP发生AMI的病例多为慢性ITP，多数患者存在心脑血管高危因素，部分患者成功接受了经皮冠状动脉介入术（PCI）。结论ITP合并AMI虽然发生率低，但需要警惕存在心血管高危因素的ITP患者，治疗上可行PCI术。

Objection To discuss the pathogenesis, clinical manifestation, treatment and prevention of acute myo- cardial infraction （AMI） in patients with primary immune thrombocytopenia （ITP）. Methods Clinical data were col- lected from a newly diagnosed AMI patient with ITP, including clinical characteristics, diagnostic procedures and follow - up visit information and related literature was reviewed. Then, high risk factors involved and consequent treatment regi- men were summarized. Results This ITP patient had high risk factors of AMI. Currently, AMI patients tended to suffer from chronic ITP and most of them show high risk factors of coronary artery. Part of these patients received percutaneous coronary intervention successfully. Conclusion Although AMI rarely occur in ITP patients, more attention must be giv- en to the patients with risk factors of coronary artery and percutaneous coronary intervention may be feasible.