重症急性胰腺炎早期应用肠内营养临床疗效分析

Clinical effect of early enteral nutrition in patients with severe acute pancreatitis

目的观察重症急性胰腺炎(SAP)患者早期肠内营养(EEN)治疗的疗效。方法将65例SAP患者随机分成EEN组(33例)和TPN组(32例)。EEN组患者采取早期EEN+TPN治疗,并逐渐减少TPN的用量,直至停止TPN;TPN组患者采取TPN治疗。观察2组患者腹痛的缓解时间、住院期间花去的费用、住院的天数以及是否出现并发症。结果:2组患者通过营养支持后EEN组的腹痛缓解时间、住院时间、花去费用以及并发症发生率均低于TPN组(P<0.05)差异具有统计学意义。结论 EEN治疗可显著提高SAP患者的治愈率,降低感染率及并发症的发生,并缩短住院时间。

Objective To observe the curative effect of early enteral nutrition support on severeacute pancreatitis （SAP）. Methods 65 patients with SAP were randomly divided into EEN group （33 cases） and TPN group （32 cases）. EN group of patients to take early EEN ＋ TPN treatment, and gradually reduce the amount of TPN, until the cessation of TPN ; TPN group of patients to take TPN treatment. The remission time of abdominal pain, the cost of hospitalization, the days of hospitalization and the complications of the 2 groups were observed. Results 2 groups of patients with abdominal pain relief time, length of stay, hospital stay, cost of hospi- talization and complications of EEN group were significantly lower than those in group TPN （ P 〈 0. 05 ）, and the difference was statisti- cally significant. Conclusion EEN treatment can significantly improve the cure rate of patients with SAP, reduce the infection rate and the incidence of complications, and shorten the hospital stay.