头痛宁胶囊联合黛力新治疗慢性偏头痛36例

Thirty Six Cases with Chronic Migraine Treated with Toutongning Capsules Combined with Deanxit

目的:观察头痛宁胶囊联合黛力新治疗慢性偏头痛的疗效。方法:选取2010年1月—2013年12月本院门诊及住院的慢性偏头痛患者69例,按随机数字表法分为单药组33例和联合组36例。单药组给予头痛宁胶囊口服治疗,联合组给予头痛宁胶囊联合黛力新治疗。结果:联合组治疗后每月头痛发作频率、头痛持续时间及头痛程度均优于单药组(P<0.05);联合组有效率为86.11%,单药组有效率为77.42%,联合组优于单药组(P<0.05);单药组不良反应发生率27.78%,联合组不良反应发生率12.90%,联合组优于对照组(P<0.05)。结论:头痛宁胶囊联合黛力新治疗慢性偏头痛疗效显著。

Objective： To observe the clinical effects of Toutongning Capsules combined with Deanxit on chronic migraine. Methods：Totally 69 patients with chronic migraine admitted into this hospital between January 2010 and December 2013 were randomized into single-drug group（ 33 cases） and combined group（ 36 cases）. Single-drug group were given Toutongning Capsules while combined group were given Toutongning Capsules combined with Deanxit for the treatment. Results： The onset rate of headache monthly,duration of headache and severity of headache in combined group were superior than those in Single-drug group（ P 〈 0. 05）.The effective rate was 86. 11% in combined group and 77. 42% in single-drug group; combined group were superior to single-drug group（ P 〈 0. 05）. The occurrence rate of adverse reaction was 27. 78% in single-drug group and 12. 90% in combined group;combined group were superior to single-drug group（ P 〈 0. 05）. Conclusion： Toutongning Capsules combined with Deanxit has significant therapeutic effects on chronic migraine.