子宫内膜息肉电切术后应用曼月乐环及药物预防复发的比较研究

Effects of Mirena Ring and Medication in Prevention of Endometrial Polyps after Resection of Endometrial Polyps: a Comparative Study

目的对比研究子宫内膜息肉电切术后应用曼月乐环及药物预防复发的效果。方法在我院收治的子宫内膜息肉患者中选择予以宫腔镜下息肉切除术治疗的126例患者,其中,有45例患者在息肉切除后放置曼月乐环(LNG-IUS),设为曼月乐组;有41例患者在息肉切除后应用激素类药物治疗,设为治疗组;剩余40例患者在息肉切除后未做其他处理,为对照组。三组患者治疗后均随访24个月,对比三组的治疗结果。结果随访期间曼月乐组和治疗组的复发率、月经失血量评分(PBAC)和子宫内膜厚度低于对照组,而血红蛋白水平高于对照组,P<0.05,术后曼月乐组和治疗组不同时间的上述指标无明显差异,P>0.05。在随访期间曼月乐组有2例患者因复发取出曼月乐环,42例患者环位良好,1例患者脱落。结论子宫内膜息肉电切术后应用曼月乐环或者激素类药物均可有效地降低子宫内膜息肉的复发率,值得临床推广。

Objective To compare the efficacy of Mirena ring and medication in preventing the recurrence of endom- etrial polyps after resection of endometrial polyps. Methods 126 patients with endometrial polyps were treated with hystero- scopic polypectomy. Forty -five patients underwent endoscopic polypectomy （LNG -IUS） after polypectomy. Forty -one pa- tients were treated with hormone therapy after polypectomy. The other 40 patients were treated without polyps after resection. Three groups of the patients were followed up for 24 months after treatment, compared to the treatment of three groups. Re- suits The relapse rate, menstrual blood loss score （PBAC） and endometrial thickness of the Mirena group and the treatment group were lower than those of the control group, while the hemoglobin level was higher than that of the control group （ P 〈 0. 05 ）. There were no differences in the above - mentioned indicators at different time between the treatment group and other groups （P 〉 0. 05 ）. During the follow- up period, Mirena rings in 2 patients were taken out and the ring＇s positions in 42 patients were right, and the ring in 1 patient got detached. Conclusion The application of Mirena ring or hormone drugs af- ter endometrial polyp can both effectively reduce the recurrence rate of endometrial polyps and they are worthy of clinical pop- ularization.