肠腔灌洗术在直肠癌保肛根治术中的应用进展

Application Progress of Intestinal Lavage in Anus-preserving Resection for Rectal Cancer

肿瘤脱落细胞种植导致直肠癌患者术后吻合口复发,而合理应用肠腔灌洗术能明显减少肿瘤细胞,降低局部复发率。近几年来,肠腔灌洗术被越来越多的学者提出并投入研究使用,利用0.9%氯化钠注射液、聚维酮碘进行肠腔灌洗已取得了确切的灌洗效果,两者均能明显降低肿瘤脱落细胞的数量和直肠癌患者术后的复发率。但是,直肠癌化疗药物是否能应用于灌洗,其灌洗效果是否优于0.9%氯化钠注射液和聚维酮碘,仍有待进一步研究。

Large number of exfoliated tumor cells may cause postoperative rectal anastomotic recurrence; reasonablyapplied intestinal lavage can significantly reduce the number of residual tumor cells and the local recurrence. In recentyears, intestinal lavage has been proposed and put in use by more and more researchers. Using 0. 9% sodium chloride solu-tion（saline） and povidone iodine for intestinal lavage has achieved the reliable effect for irrigation,both of them can reducethe number of exfoliated tumor cells and decrease the recurrence rate of rectal cancer after surgery. However, whether che-motherapeutic drugs for rectal cancer can be used for the irrigation and whether the irrigation effect is better than the use ofsaline and povidone iodine still need further studies.