腹膜透析在医院获得性急性肾损伤中的可行性研究进展

Feasibility Study Progress of Peritoneal Dialysis in Hospital-acquired Acute Kidney Injury

医院获得性急性肾损伤(HA-AKI)的发病率呈不断上升趋势,目前临床最常用的治疗方法为体外血液净化(EBP)。尽管腹膜透析(PD)也是HA-AKI的有效治疗方式,且利用自身腹膜作为半透膜,更接近生理状态,但其临床用应用一直未得到重视。PD与EBP对HA-AKI的治疗作用相当,且PD更简单、经济,无需抗凝,尤其对血流动力学不稳定者有一定的优势,预示着其有很大的发展潜力。

The incidence of hospital-acquired acute kidney injury（HA-AKI） shows a rising trend. Extracorporeal bloodpurification（EBP） remains the most common treatment for HA-AKI. Peritoneal dialysis （PD） is also an effective treatmentfor HA-AKI, which uses its own peritoneum as semipermeable membrane, that is much closer to physiological status.However,the apphcation of PD in HA-AKI has never been emphasized. Therapeutic effect of PD and EBP on HA-AKI is notsignificantly different, and PD is technically simpler, costs less, and free of anticoagulation, which has special advantages forpatients with hemodynamic instability,indicating its great potential.