缩宫素单用与联合米索前列醇用于足月妊娠引产效果比较

Effect of Oxytocin and Misoprostol on Induction of Labor in Full-Term Pregnancy

目的对比缩宫素与米索前列醇在足月妊娠引产中的应用效果,以指导临床合理用药。方法选取医院妇产科2016年1月至12月收治的足月妊娠引产孕妇80例,采用便利抽样法分为对照组与观察组,各40例。对照组给予常规缩宫素引产,观察组在给予缩宫素基础上加用米索前列醇,对比两组的引产成功率与分娩情况。结果观察组总成功率为95.00%,明显高于对照组的75.00%,差异有统计学意义(P<0.05);治疗后,观察组的临产时间、分娩时间与总产程均明显短于对照组,差异有统计学意义(P<0.05)。结论在足月妊娠引产中联合小剂量缩宫素与米索前列醇,可明显缩短产程,诱发宫缩,提高引产成功率,值得临床推广。

Objective To compare the Oxytocin and the application effect of Misoprostol in full- term pregnancy induced labor, in order to guide clinical rational drug use. Methods 80 cases of induction of full- term pregnant women in the hospital from January to December 2016 were selected and divided into the control group and the observation group using convenience sampling method, 40 cases in each group. The control group used conventional Oxytocin; on this basis, the observation group combined with Misoprostol. The success rates of induction and delivery in the two groups were compared. Results The total success rate of the observation group was 95.00%, which was significantly higher than 75.00% of the control group（ P 〈 0. 05）. After treatment, the labor time, delivery time and total labor rate of the observation group were significantly shorter than the control group（ P 〈 0.05）. Conclusion Low dose oxytocin combined with misoprostol in full- term pregnancy can shorten the labor course, induce contractions and improve the success rate of induction and labor, which is worthy of clinical promotion.