喜炎平注射液儿科门诊应用合理性分析

Application Rationality of Xiyanping Injections in Pediatric Outpatients

目的调查医院儿科门诊使用喜炎平注射液的情况,以规范和指导临床合理用药,为儿童用药监护提供依据。方法随机抽取医院2016年7至12月每月3 d儿科门诊使用喜炎平注射液的处方354张,回顾性分析方中喜炎平注射液的使用情况。结果 99.72%使用喜炎平注射液的患儿符合说明书适应证;静脉给药的溶剂、疗程均较合理;只有1例用药剂量不足;联合用药时,仅47.95%的输液接瓶使用了冲管液;改变药品说明书用药途径为雾化给药方式的占77.97%。结论医院儿科喜炎平注射剂临床使用总体较为规范,且相对安全。应加强超药品说明书用药的规范化管理,保障儿童用药安全。建议生产企业开展该注射液雾化给药的安全性评价,规范儿童雾化吸入给药的剂量和频次。

Objective To assess the clinical application of Xiyanping Injection in pediatric outpatient,and to provide a reference for rational drug use in clinical institute as well as strengthening the monitoring of pediatric medication. Methods 354 outpatient prescriptions with Xiyanping Injection from July to December 2016 in the hospital were randomly selected. Retrospective analysis was conducted on the application situation of Xiyanping Injection. Results Of all the drug use,99. 72% had met the medication indication; the solvent and treatment of intravenous administration was relatively reasonable; only 1 case showed lack of dosage; for combination of other drugs,only 47. 95% of the infusion bottle used the flushing fluid; changing the route of administration for atomizing accounted for 77. 97%.Conclusion The application of Xiyanping Injection in pediatric outpatients of the hospital is rational on the whole and relatively safe. Rational use of the drug should be strengthened and regulated to ensure safe medication in children. It is recommended that the production enterprises carry out the safety evaluation of the atomized administration of the injections and standardize the dose and frequency of the inhalation of the children.