半胱氨酸蛋白酶抑制剂SN的功能及其与肿瘤的关系

Function of Cystatin SN and its relationship with tumors

半胱氨酸蛋白酶抑制剂SN（Cystatin SN）是一种由CSTl编码的分泌型蛋白，具有促进细胞衰老凋亡的活性，在蛋白水解酶活性调控中发挥重要作用。许多研究发现，Cystatin SN在多种类型肿瘤中存在异常表达，且与肿瘤发生、发展密切相关。Cystatin SN可能在肿瘤的诊断和预后评估中发挥重要作用。

Cysteine protease inhibitor SN （Cystatin SN） is a secretory protein encoded by CST1, with the promotion of cell senescence and apoptosis activity, playing an important role in the regulation of proteolytic activity. Many studies have found that Cystatin SN is abnormally expressed in various kinds of tumors, and is closely related with the tumorigenesis and progression. Cystatin SN may play an important role in the diagnosis and prognosis of tumors.