胃癌的分子分型研究进展

Molecular classification of gastric cancer

胃癌具有高度异质性，传统的组织病理学分型对临床工作的指导意义十分有限。随着分子检测技术的飞速发展，以各种分子为依据进行的分型能够对胃癌的临床治疗与预后提供更精准的帮助。胃癌分子分型包括Tan分型、Lei分型、克隆性分型、癌症基因组图集（TCGA）分型和亚洲癌症研究组织（ACRG）分型等，这些分型各具特色，各有优劣。

Gastric cancer has high heterogeneity, and the traditional histopathologic classification has a limited significance for clinical work. Along with the dramatic development of molecular detection technology, it may be much more helpful for the treatment and prognosis to use the molecular classifications. Recently, there have been many researches on the molecular classification of gastric cancer, such as Tan type, Lei type, clona- lity type, The Cancer Genome Atlas （TCGA） type, Asian Cancer Research Group （ACRG） type, and so on. All of these molecular classification methods have respective advantages and disadvantages.