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放射性心脏损伤发生机制及潜在干预措施的研究进展 被引量:3

Progress on Mechanism of Radiation Induced Heart Disease and Its Potential Interventions
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摘要 放射性心脏损伤是胸部肿瘤放射治疗中的常见并发症,其发生机制为线粒体等细胞微观结构改变、毛细血管受损、炎症与纤维化,临床相关影响因素有放射物理、药物联合使用、心肺相互作用,文章在此基础上对可能的干预措施进行讨论。 Radiation induced heart disease is a common complication of thoracic radiotherapy. Its mechanism includes mitochondrial damage,capillary damage,inflammation and fibrosis. Physical features of radiation,combination of drugs use and heart-lung interaction are important influencing factors clinically. This article proposes some potential interventions based on these influencing factors.
机构地区 浙江省肿瘤医院
出处 《肿瘤学杂志》 CAS 2017年第3期227-232,共6页 Journal of Chinese Oncology
关键词 放射性心脏损伤 放射疗法 干预 radiation induced heart disease radiotherapy intervention
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  • 1梅审之,刘秋芳,谭丽,孙英.86例胸部肿瘤放射治疗心电图改变[J].现代肿瘤医学,2005,13(3):410-411. 被引量:10
  • 2姜志荣,吕慧霞,刘培京,李大海,何信佳.超声心动图评价蒽环类药对乳腺癌患者心脏毒性[J].中国医学影像技术,2005,21(8):1209-1212. 被引量:9
  • 3范风云,石梅,张丙芳.放射性心脏损伤及防护的研究进展[J].心脏杂志,2006,18(6):721-723. 被引量:29
  • 4张卓,邹丽娟,礼广森,夏稻子,王月爱,崔洪岩.定量组织速度成像评价左乳腺癌患者放疗左心室功能的变化[J].中国超声医学杂志,2007,23(3):185-187. 被引量:5
  • 5Franken NA, Camps JA, van Ravels, FJ. Comparison of in vivo cardiac function with ex vivo cardiac performance of the rat hear after irradiation. Br J Radiol,1997,70:1004-1009.
  • 6Lefrak EA, Pitha J, Rosenheim S, et al. A clinicopathologic analysis of adriamycin cardio-toxicity. Cancer,1973,32:302-314.
  • 7Giraud P, Cosset JM. Radiation toxicity to the heart:physiopathology and clinical data. Bull Cancer,2004,91 Suppl 3:147-153.
  • 8Steinherz LJ, Steinherz PG, Tan CT, et al. Cardiac toxicity 4 to 20 years after completing anthracycline therapy. JAMA,1991,266:1672-1677.
  • 9Gladstone DJ, Flanagan MF, Southworth JB, et a1. Radiation-induced cardiomyopathy as a function of radiationbeam gating to the cardiac cycle. Phys Med Biol,2004,49:1475-1484.
  • 10Evans ES, Prosnitz RG, Yu X, et al. Impact of patient-specific factors, irradiated left ventricular volume, and treatment set-up errors on the development of myocardial perfusion defects after radiation therapy for left-sided breast cancer. Int J Radiat Oncol Biol Phys,2006,66:1125-1134.

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