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治疗方式对外阴鳞癌ⅠB期复发的影响

Impact of Different Surgical Modalities on Recurrence in Patient with Squamous Cell Carcinoma of the Vulvar Stage ⅠB
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摘要 [目的]探讨外阴鳞癌ⅠB期不同治疗方式的复发情况。[方法]对30例确诊并治疗的外阴鳞癌ⅠB期进行回顾性分析,用Kaplan-Meier方法进行预后比较。[结果]外阴鳞癌ⅠB期1年复发率为26.67%(8/30)。对于仅行手术治疗者,外阴局部扩大切除术患者复发率为60%(3/5),而外阴广泛切除术+腹股沟淋巴结清扫者为23.0%(3/13),差异具有统计学意义(P=0.045)。对于行外阴广泛切除术+腹股沟淋巴结清扫术者23例,有复发高危因素如病理分化差、瘤体大等共14例,行外阴广泛切除术+腹股沟淋巴结清扫术+放疗和(或)化疗者1年复发率为10%(1/10),而行外阴广泛切除术+腹股沟淋巴结清扫术者为50%(2/4),1年复发率差异具有统计学意义(P=0.03)。[结论]对于ⅠB期外阴鳞癌,尽可能行腹股沟淋巴结清扫,对于有高危因素者,手术结合放疗或(和)化疗能降低其近期复发率。
出处 《肿瘤学杂志》 CAS 2017年第3期238-240,共3页 Journal of Chinese Oncology
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