不同方法治疗口腔种植体周围黏膜炎的临床疗效

Analysis of the clinical efficacy in different treatments for peri-implant mucositis

目的:分析不同方法治疗口腔种植体周围黏膜炎的临床疗效。方法:选取64例种植体周围黏膜炎患者,随机分为观察组和对照组,分别使用盐酸米诺环素软膏和2%碘甘油治疗,比较两组患者的临床疗效,如:基线、治疗后1周、3周、6周探诊深度(probing depth,PD)、菌斑指数(plaque index,PLI)、龈沟出血指数(sulcus bleeding index,SBI)。结果:观察组患者的临床疗效总有效率为100.00%,高于对照组患者的90.00%(P<0.05)。观察组患者的显效率为76.32%,而对照组患者的显效率仅为40.00%。治疗后1周、3周、6周PLI、PD、SBI均改善,差异具有统计学意义(P<0.05),治疗后1周两组患者的PLI无差异(P>0.05),观察组患者PD、SBI值低于对照组患者,治疗后3周、6周观察组患者PLI、PD、SBI值均低于对照组患者(P<0.05)。结论:盐酸米诺环素软膏较2%碘甘油治疗种植体周围黏膜炎可明显提高临床疗效,值得进一步在临床上推广。

Objective：To compare the clinical efficacy of different methods in the treatment of peri - implant mucositis. Methods ：64 patients with peri - implant mucositis were randomly selected and divided into the observation group and the control group. The two groups were treated with minocycline hydrochloride ointment and iodine glycerin 2 %, respectively. The clinical efficacy, baseline, probing depth （PD） 1 week, 3 weeks, 6 weeks after treatment, plaque index （PLI） and sulcus bleeding index （SBI） were compared between the two groups. Results： The total effective rate was 100.00% in the observation group and 90.00 % in the control group. The markedly effective rate in the observation group was 76.32 %, while that in the control group was only 40.00 %. The difference of PLI, PD and SBI between the observation group and the control group was sta- tistically significant（ P 〈0.05 ）. There was no significant difference in PLI between the two groups 1 week after the treatment （ P 〉 0.05 ）, and PD and SBI were significantly lower than those in the control group （ P 〈 0.05 ）. The PLI, PD and SBI of the observation group at 3 and 6 weeks after treatment were significantly lower than those in the control group （ P 〈 0.05 ）. Conclusion： Minocycline hydrochloride ointment is more effec- tive than iodine glycerin 2 % in the treatment of peri - implant mucositis. It is worthy to be further popularized in clinical practice.