摘要
目的探讨血清尿酸(UA)及β2微球蛋白(B2M)水平与冠脉病变程度的关系。方法根据Gensini评分冠心病(CHD)患者被分为A组(305例、<20分),B组(203例、20~40分),C组(153例、>40分),经冠脉造影被排除CHD为对照组(244例),分析UA及B2M水平。结果 CHD组UA(353±41)μmol/L及B2M(2.41±0.73)mg/L水平高于对照组(271±38)μmol/L、(1.73±0.49mg/L)(P<0.05)。血清UA及B2M在A组(318±32)μmol/L、(2.12±0.41)mg/L、B组(341±37)μmol/L、(2.53±0.68)mg/L、C组(382±41)μmol/L、(3.13±1.12)mg/L比较差异有统计学意义(P<0.01),与Gensini积分均呈正相关(P<0.01)。结论 UA及B2M水平与冠脉病变程度有一定的相关性。
Objective To investigate the relationship between serum uric acid （ UA ） and beta 2 microsphere protein （B2M）levels and the severity of coronary artery disease. Methods Coronary heart disease（CHD）patients were divided into group A（305 cases,〈20 scores）,group B（203 cases、20-40 scores）,group C（153 cases、〉40 scores）according to Gensini score. CHD was excluded by coronary angiography as the control group（244 Cases）. UA and B2M levels were analyzed. Results The UA（353 ±41）μmol/L and B2M（2.41 ±0.73）mg/L level of CHD group were higher than thoseof the control group（271 ±38）μmol/L、（1. 73 ± 0. 49）mg/L（P〈0. 05）. The comparison of serum UA and B2M in group A（318 ± 32）μmol/L、（2. 12 ± 0. 41） mg/L、group B（341 ±37）μmol/L、（2.53 ±0.68）mg/L、group C（382 ±41）μmol/L、（3.13 ±1.12）mg/L,the differences were statistically significant（P〈0. 01）,and were all positively correlated with Gensini score（P〈0. 01）. Conclusion There is a cer-tain correlation between the levels of UA and B2M and the severity of coronary artery disease.
出处
《四川医学》
CAS
2017年第3期257-259,共3页
Sichuan Medical Journal
基金
四川省卫生与计划生育委员会科研课题(编号:150097)
