117例肝炎肝硬化患者的肝功能检验结果临床分析与研究

Clinical Analysis and Study on the Results of Liver Function Tests in 117 Patients with Hepatitis Cirrhosis

目的:分析肝炎肝硬化患者的肝功能检验结果。方法:选取2015年3月-2016年4月笔者所在医院收治的117例肝炎肝硬化患者和70例来笔者所在医院体检的正常者,对两组研究对象血清胆碱酯酶的活性、血清胆固醇水平、白蛋白水平和总胆汁酸水平进行测定,进行相关对比和评定。结果:A级患者的血清胆碱酯酶活性和白蛋白水平高于B级患者及C级患者;总胆汁酸水平低于B级患者及C级患者,差异有统计学意义(P<0.05)。但A级患者的血清胆固醇水平与B级患者对比,差异无统计学意义(P>0.05),A级患者的血清胆固醇水平与C级患者对比,差异有统计学意义(P<0.05)。观察组患者的血清胆碱酯酶活性、白蛋白水平、血清胆固醇水平均低于对照组,而总胆汁酸水平高于对照组,差异有统计学意义(P<0.05)。结论:肝功能相关指标的检测,对临床正确诊断病情有重要意义。

Objective： To analyze the results of liver function tests in patients with hepatitis cirrhosis.Method： From March 2015 to April 2016, 117 cases of hepatitis cirrhosis patients in our hospital and 70 normal people were selected.The serum cholinesterase activity, serum cholesterol level, albumin level and total bile acid levels of the two groups were measured and given related comparison and evaluation.Result： The activity of cholinesterase and albumin in patients with grade A were higher than those in grade B and grade C, and the level of total bile acid was lower than that of grade B and grade C patients, and the differences were statistically significant（P〈0.05）.However, there was no significant difference in the level of serum cholesterol between grade A and grade B patients（P〉0.05）. The level of serum cholesterol in patients with grade A was significantly higher than that in patients with grade C（P〈0.05）.The serum cholinesterase activity, albumin levels, serum cholesterol level of the the observation group were lower than those of the control group, while the total bile acid level was higher than the control group, the differences were statistically significant（P〈0.05）.Conclusion： The detection of liver function related indexes has important significance for the correct diagnosis of the disease.