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晚期口腔颌面-头颈肿瘤单抗靶向治疗的分析 被引量:3

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摘要 目的:分析研究晚期口腔颌面-头颈肿瘤采取单抗靶向治疗的方法以及治疗效果,为临床提供有力的依据。方法:选取重庆医科大学附属口腔医院颌面外科在2007年12月-2015年12月所收治的晚期口腔颌面-头颈肿瘤患者104例的资料开展回顾性分析,104例患者全部接受单抗靶向治疗,统计104例患者的治疗效果。结果:104例患者完成化疗疗程,尼妥珠应用2~8次,对患者进行为期半年的随访显示,104例患者中60例患者获得彻底手术治疗,完全缓解10例,部分缓解50例,10例无法评价,病灶稳定29例,疾病进展5例;104例患者的近期缓解率为57.7%,患者中5例存在轻微皮疹,其余患者没有出现严重不良反应。结论:对于晚期口腔颌面-头颈肿瘤患者采取单抗靶向治疗,患者对于尼妥珠存在良好的耐受性,能够提升患者化疗敏感性,使大部分患者重新获得手术治疗机会,治疗效果显著,应该在临床中大力推广使用。
作者 曾峥
出处 《中外医学研究》 2017年第9期105-106,共2页 CHINESE AND FOREIGN MEDICAL RESEARCH
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