脑梗死后预测出血性转换发生的影像研究进展

The progress of imaging study on predicting the occurrence of hemorrhagic transformation after cerebral infarction

脑梗死后引起脑组织损伤、血脑屏障的破坏,导致脑梗死后出血性转换(HT)的发生。利用影像检查方法可动态观察缺血区细胞缺血缺氧情况、微血管通透性的变化以及侧支循环的建立,从而预测HT的发生。目前有CT灌注(CTP)成像、MR灌注成像以及多种MRI序列可运用于此预测。就CTP、MRI用于预测脑梗死后HT发生的研究进行综述,为病人个性化治疗提供参考。

Cerebral infarction causes brain tissue and blood-brain barrier damages, leading to hemorrhagic transformation（HT）. The degree of cerebral ischemia and hypoxia, the changes of micro vascular permeability and the establishment of collateral circulation in ischemic region can be observed dynamically by image examination to predict the occurrence of HT. At present, CT perfusion imaging（CTP）, magnetic resonance perfusion imaging and a variety of magnetic resonance scan sequences are available for this prediction. We reviewed the studies of the new development in CTP and MRI in predicting HT after cerebral infarction in order to provide a reference for personalized treatment.