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多囊卵巢综合征患者改良超长方案启动日血清LH水平与IVF-ET结局的关系 被引量:5

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摘要 目的探讨改良超长降调节方案启动日黄体生成素(LH)水平与多囊卵巢综合征(PCOS)患者体外受精-胚胎移植(IVF-ET)技术结果的关系。方法回顾分析2013年1月至2016年1月采用改良超长方案的180例PCOS患者临床资料,按照启动日LH水平分为A、B两组。A组130例,0.5 mIU/ml〈LH≤3.0 mIU/ml;B组50例,LH≤0.5 mIU/ml。比较两组人绝经期促性腺激素(HMG)用药量及时间、取卵数、受精率、优胚率、卵巢过度刺激综合征(OHSS)发生率、取消周期率、胚胎种植率、临床妊娠率、早期流产率及异位妊娠率等。结果A组的HMG用量及时间、取卵数均低于B组(P〈0.05);A组胚胎种植率、临床妊娠率均明显高于B组(P〈0.05);受精率、优胚率、OHSS发生率、取消周期率及早期流产率等两组差异均无统计学意义(P〉0.05);两组患者均未出现异位妊娠。结论改良超长方案PCOS患者启动日适当的LH水平有助于改善临床结局,LH〉0.5 mIU/ml可作为启动的重要参考指标。
出处 《中国医师杂志》 CAS 2017年第3期421-423,共3页 Journal of Chinese Physician
基金 河南省医学科技攻关计划项目(201602359)
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