老年COPD合并呼吸衰竭患者综合治疗的临床研究

Clinical study on combined treatment in elderly COPD patients with respiratory failure

目的探讨老年COPD合并呼吸衰竭患者综合治疗的临床效果。方法选取2012年7月至2013年12月在商丘市第一人民医院急诊科治疗的84例COPD并发呼吸衰竭患者作为探讨对象,按照治疗方式的不同将84例患者分为常规组(30例)和综合疗法组(54例),常规组患者予以解痉平喘、祛痰、利尿、支气管扩张剂、抗感染等对症治疗,综合组患者在对照组基础上结合无创呼吸机治疗,并比较两组患者的临床治疗效果。结果经过治疗后,综合组患者临床总有效率为90.7%,常规组患者临床总有效率为70.0%,综合组患者临床有效率明显高于常规组,两组比较差异具有统计学差异(P<0.05);此外综合组患者住院时间、ICU时间以及血气指标变化情况均显著优于常规组,两组比较差异具有统计学意义(P<0.05)。结论综合疗法在治疗COPD并发呼吸衰竭上其临床总有效率明显升高,且可有效降低患者治疗时间和改善血气指标,该方法具有临床推广应用价值。

Objective To explore the clinical effect of combined treatment in elderly COPD patients with respiratory failure. Methods Selected July 2012-December 2013 in 84 cases of COPD in our hospital emergency department treatment of patients with respiratory failure as explore objects,according to the different treatment of the 84 patients were divided into control group（ 30 cases） and the combination therapy group（ 54 cases）,conventional group of patients to be antispasmodic,expectorant,diuretic,bronchodilators,antibiotics and other symptomatic therapy,a comprehensive set of non-invasive ventilation in patients in combination therapy in the control group on the basis of clinical effect and two groups were compared. Results After treatment,patients with a comprehensive set of clinical total effective rate was 90. 7%,routine clinical patient group,the total effective rate was 70. 0%,the comprehensive clinical patient group was significantly higher than that of the conventional group,with a statistically significant difference between the two groups（ P＜0. 05）,in addition a comprehensive group of hospital stay,ICU time and blood gas changes were significantly better than those the conventional group,the difference was statistically significant（ P＜0. 05）. Conclusion Combination therapy in the treatment of COPD with respiratory failure on total clinical efficiency was significantly increased,and can effectively reduce patients＇ treatment time and improve blood indicators,this method has clinical application value.