牙周基础治疗联合替硝唑胶囊治疗糖尿病性牙周炎的效果及安全性分析

Analysis of periodontal therapy combined with tinidazole capsule treatment of diabetic periodontitis efficacy and safety

目的探究牙周基础治疗联合替硝唑胶囊治疗糖尿病性牙周炎的效果及安全性。方法选取本院于2014年3月至2016年3月收治的114例糖尿病性牙周炎患者进行回顾性分析,按治疗方法不同设为对照组(61例)与研究组(53例);前者予以牙周基础治疗,后者予以牙周基础治疗联合替硝唑胶囊治疗,观察两组治疗前后hs-CRP、Hb A1c水平,牙周指标变化及不良反应。结果经治疗后,两组hsCRP、Hb A1c水平均有降低,但研究组较对照组低(P<0.05);两组牙周指标均有所改善,但研究组牙周指标比对照组优(P<0.05);研究组不良反应比对照组少(P<0.05)。结论牙周基础治疗联合替硝唑胶囊用于治疗糖尿病性牙周炎可有效降低hs-CRP、Hb A1c水平,改善牙周指标,减少不良反应,效果显著,值得推广。

Objective To explore the periodontal therapy combined with tinidazole capsule treatment of diabetic periodontitis efficacy and safety.Methods 114 cases of diabetic periodontitis patients were retrospectively analyzed in our hospital during March 2014-March 2016,according to the different treatment methods to the control group（61 cases） and study group（53 cases）：the former to be periodontal treatment,the latter shall periodontal therapy combined with tinidazole capsule treatment,observation hs-CRP,Hb A1 c levels,periodontal index and adverse reactions before and after treatment.Results After treatment,both groups hsCRP,Hb A1 c levels were reduced,but the study group reduced faster than the control group（P〈0.05）：two groups of periodontal indicators have improved,but the study group than periodontal index excellent control group（P〈0.05）：study groups fewer adverse reactions than the control group（P〈0.05）.Conclusions Periodontal therapy combined with tinidazole capsule for the treatment of diabetic periodontitis can effectively reduce hs-CRP,Hb A1 c levels,improve periodontal index,reduce adverse reactions,the effect is significant,which is worth promoting.